Vaccine Development – Lorenzo Giacani (Univ Wash) moderator
08:00–08:20
Protective Immunity and Syphilis Vaccine Development: the Early Years
Prof. Justin David Radolf (UConn Health and Connecticut Children's, Professor of Medicine; Pediatrics; Molecular Biology and Biophysics; Genetics and Genome Sciences; and Immunology; Director of Research Department of Medicine; Senior Scientific Advisor, Connecticut Children's Research Institute)
08:20–08:40
Syphilis Vaccine Development - Platform for Protection
Prof. Caroline Cameron (University of Victoria, Professor)
08:40–09:00
Engineering Multi-Valent Scaffolds Displaying Treponema Pallidum Outer Membrane Protein ECL Candidate Syphilis Vaccinogens
Prof. Melissa J. Caimano (UConn Health, Professor)
09:00–09:20
Challenges, Controversies and Opportunities in Syphilis Vaccine Research
Prof. Feijun Zhao (Affiliated Changsha Central Hospital of University of South China, Professor)
09:20–09:45
Open Session: Announcements/Topics for wrap-up session
In vitro cultivation – Kelly Hawley (CT Children's/UConn Health) moderator
10:05–10:25
The expanding scope of Treponema pallidum in vitro culture utilization
Steven J. Norris, Ph.D. (Dept. of Pathology & Laboratory Medicine, UTHealth Houston McGovern Medical School, Professor & Vice Chair for Research)
10:25–10:45
In vitro host interactions of Treponema pallidum: Implications for translational research
Prof. Linda Grillova (Wellcome Sanger Institute, Cambridge, UK, Career Development Fellow)
10:45–11:05
Antibiotic susceptibility testing using the in vitro cultivation system for Treponema pallidum
Prof. Lorenzo Giacani (University of Washington, Professor)
11:05–11:25
Combining the OMPeome structural map and in vitro cultivation to elucidate antibody interactions with T. pallidum surface proteins
Kelly L. Hawley, Ph.D (CT Children's | UConn Health, Assistant Professor)
11:25–14:00
Working Lunch: Diagnostics Networking
Implementation/Community engaged efforts - Mitch Matoga (UNC Malawi) and Zou Huachun (Fudan Univ) moderators
14:00–14:20
Participatory syphilis research: Ask not what syphilis can you do for you, but what you can do for syphilis
Prof. Joseph Tucker (UNC and LSHTM, Professor of Medicine and Global Health)
14:20–14:40
Implementation practice and research in HPV vaccination
Prof. Dan Wu (Nanjing Medical University, Professor)
14:40–15:00
Willingness to Participate in Syphilis Vaccine Research in Malawi: Considerations for Community Engagement
Mitch Matoga, Ph.D (University of North Carolina Project Malawi, Director of STI Research and Clinical Services)
15:00–15:20
Can a Chatbot Fight Stigma? AI for Promoting STD Testing and Reframing Sexual Health Communication
Prof. Bolin Cao (Shenzhen University, Associate Professor)
15:20–16:30
Panel Discussion: Wrap-up/ Action Plan
